Piezo nanoactuator w/o a flexture

This might be a rather silly question, I apologize to everyone. I have a very small sample about 5x5x1 mm (a flat disk) which I would like to move by 0-5 micron along one axis under my microscope (already controlled in XYZ by a coarse flexure stage). I am thinking to use a PZT 5-mm crystal as an actuator and drive it with 0-150V DC power. Do I really need to design a flexure stage (or a roller-bearing stage) around the PZT crystal, or would it be silly to just glue the sample holder directly to the piezo, w/o any flexure guides?

If you have got only one sample then gluing it to the piezo is simple and shoild work. Changing samples would be a pain.

Piezo actuators are often added in the main actuator system, sitting between a screw and the moving stage, or between the screw mount and the stage body. Is there somewhere like that where you could fit the piezo in your system?

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Yes, there is a basic small XYZ stage controlled with fine-pitch screws, with the Z coupled to a stepper motor, and I was going to add the piezeo on top of that. I was then going to glue a magnetic steel adapter to the piezo, and the sample itself is that disk I mentioned. So, I would not have to glue the sample each time.