Unfortunately the Pi5 introduced some changes that are not compatable with the OpenFlexure OS. The installation notes specify Pi3 or 4. Pi2 are still compatable with the software I think but are significantly more sluggish. We only have electronics drawers to fit Pi3 and Pi4.
Similarly the Pi camera 2 is the only camera that is compatable with the software.
One of the key things in the robotic microscope is integration of the camera feed, including the flat field and lens shading. This allows the fast autofocus to work, and gives flat colour images that tile well. We were using picamerax, but the underlying Pi has moved to picamera2. Porting autofocus and lens shading to the new Pi software stack is in progress with the server version 3. There are some notes on that on another thread: Developing v3 of the OpenFlexure software .